A four-vehicle collision Friday evening left one car engulfed in flames on Highway180 at the interchange with Highway 41.
An unidentified woman who was driving one of the cars was transported to Community Regional Medical Center with serious injuries, said CHP Sgt. Manuel Peregrina.
It is unknown how many other people were the vehicles, Peregrina said, but there were no other serious injuries.
The cause of the 5:40 p.m. crash was not immediately determined, but distracted driving may have been involved. The roadway reopened to traffic an hour later.