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Nancy Guthrie Update: FBI's Advanced DNA Testing Could Fast-Track Break in Case

The investigation into Nancy Guthrie's disappearance could be entering a critical new phase, as attention turns to whether the FBI's advanced forensic resources may help unlock long-standing questions in the case. With key evidence still under scrutiny, the potential use of specialized DNA testing-and broader coordination across agencies-has emerged as a focal point in efforts to generate new leads.

A few days ago, ABC News reported that DNA obtained from Guthrie's home was sent to the FBI after spending several weeks being tested at a lab in Florida. Although the DNA isn't a new finding, many hope that the FBI is able to get a positive match in order to potentially identify a suspect in the case.



Related: Savannah Guthrie's Mom Update: Former FBI Agent Rejects ‘Robbery Gone Wrong' Theory

Following the news, Parade reached out to former FBI agent Greg Rogers for some insight into how long the process can take.

"The FBI lab is the best in the country," Rogers says. "A high priority case like this is prioritized and results can come back in a matter of days. We also have contacts in Mexico that will be utilized to further investigate any solid DNA testing results."

"The FBI lab has certain DNA testing capabilities that most local labs don't, such as nuclear DNA, Y-chromosome DNA, and mitochondrial DNA. Those tests are often used on shed hair fragments which are an issue in the Guthrie case," he continues, referring to the report that the piece of hair doesn't contain the root.

"The FBI's unique combination of the CODIS database, specialized testing, and national and international coordination give it the preeminent roll in working these types of cases," Rogers added.

Guthrie, 84, was last seen on Saturday, January 31. Authorities have not publicly identified any suspects in the case.

READ NEXT: Sheriff's Department Issues First Statement on Nancy Guthrie Case in Nearly a Month

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This story was originally published April 20, 2026 at 9:55 AM.

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