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Winning on the road has been a quandary the last year for the playoff-hopeful San Francisco 49ers. That's exactly where they'll be in three of the next five weeks, however, starting with Sunday's tough bout against the Green Bay Packers at legendary Lambeau Field.
Frank Gore ran for 104 yards and a touchdown, as San Francisco recorded five interceptions in a 10-6 win over the Chicago Bears at Candlestick Park.
San Francisco 49ers wide receiver Isaac Bruce is inactive for Thursday's game against the Chicago Bears due to an ankle injury.
The team that wins Thursday's primetime battle between the San Francisco 49ers and Chicago Bears at Candlestick Park will have the opportunity to kick off its weekend in a positive fashion. The loser, on the other hand, will have an extra few days to wallow in its misery before taking the field again in Week 11.
Chris Johnson ran for 135 yards and scored twice, as Tennessee got back to its winning ways in a 34-27 triumph over San Francisco.
Chris Johnson continues to live in the shadows of Adrian Peterson as the NFL's best running back, but the league's current leading rusher has earned a few headlines of his own for the Tennessee Titans.
Peyton Manning threw for 347 yards, but it was Joseph Addai that threw the game-winning TD pass to Reggie Wayne in the fourth quarter, as the Indianapolis Colts survived a tough test from the San Francisco 49ers and kept their undefeated season intact with an 18-14 victory at Lucas Oil Stadium.
San Francisco 49ers linebacker Takeo Spikes is questionable for Sunday's game at Indianapolis with a shoulder injury.
Peyton Manning and Alex Smith both have the distinction of being former No. 1 overall draft picks, but the careers of the two quarterbacks couldn't have gone any more differently up to this point.
The San Francisco 49ers signed cornerback Tarell Brown to a three-year contract extension, the team announced Wednesday.
The San Francisco 49ers put offensive lineman Tony Pashos on injured reserve Tuesday after he suffered a fractured scapula in Sunday's loss to the Texans.
San Francisco 49ers head coach Mike Singletary announced on Monday that Alex Smith will start at quarterback next week against the Indianapolis Colts.
Matt Schaub threw a pair of touchdown passes, and Steve Slaton scored twice, as the Houston Texans held off the San Francisco 49ers, 24-21, at Reliant Stadium.